Endocrine Abstracts

We present the case of a 72-year-old gentleman was admitted to our hospital with atrial fibrillation secondary to severe hypokalemia of 1.8 mmol/l, but normal serum sodium and creatinine. He had prostate cancer with extensive liver and bone metastases. After potassium supplementation 180–200 mmol/day for 10 days serum levels persisted between 2.3 and 2.9 mmol/l. During this short period he developed early Cushingoid features, jaundice and diabetes. After overnignt dexamet...

Background: Primary Hyperparathyroidism - Jaw tumour (HPT-JT) syndrome is an autosomal dominant disorder characterised by hyperparathyroidism and ossifying jaw fibromas. Inactivating germline mutations in CDC73 gene (previously known as HRPT2) is the main cause of this syndrome. There is higher incidence of parathyroid carcinoma in these individuals and also an association with other renal lesions have been described. We report a case of HPT-JT syndrome with mutation in the ex...

The aim of this audit was to assess the efficacy of vitamin D replacement therapies (oral Ergocalciferol D2 and Cholecalciferol D3) on serum Vitamin D (25(OH)D), when dispensed to endocrine outpatients. After exclusions, clinic records of 54 patients were analysed for pre- and post dosage serum 25(OH)D levels, PTH levels, total dosage given, and duration of replacement. Results: Mean total dose of D2 (n=24) was 350,000 (IU) against D3 (n=30) 305,000 (IU), with av...

A 25 year old lady was referred to the endocrine clinic after her newborn baby was noted to have respiratory problems, marked osteopenia and hypocalcemia. Further investigations on the mother showed corrected calcium of 1.11 mmol/L; however she was relatively asymptomatic. Reviewing her history in detail, she was born in Nigeria and moved to the UK 2 years prior to the presentation. She used to get intermittent cramps in her hands, legs and body since the age of 10 in addition...

Glomus jugulare tumours are rare and often difficult to manage. A small proportion of these tumours (1–3%) can cause symptoms due to catecholamine secretion. Here we describe a patient with secretory glomus jugulare tumour treated with steriotactic radio surgery and its effect on catecholamine secretion.Case report: A 39-year-old lady was referred to ear specialists with the characteristic symptoms of pulsatile tinnitus and decreased hearing in the ...

Aim: In this study we have compared the adequacy rates of FNA samples between more experienced and less experienced operators in thyroid FNA.Introduction: The prevalence of thyroid nodules is estimated to be about 4–7%, increasing up to 50% in the adult population. US guided FNA has become the preliminary investigation of choice for thyroid nodules, as it is widely available and has been proven to increase diagnostic efficacy....